Hiroshi Ishii Selected Research

Gemcitabine

1/2022	The clinical outcomes of combination chemotherapy in elderly patients with advanced biliary tract cancer: an exploratory analysis of JCOG1113.
2/2021	Randomized phase II study of chemoradiotherapy with versus without induction chemotherapy for locally advanced pancreatic cancer: Japan Clinical Oncology Group trial, JCOG1106.
1/2021	Comparison of gemcitabine-based chemotherapies for advanced biliary tract cancers by renal function: an exploratory analysis of JCOG1113.
1/2021	A randomized, double-blind, phase II study of oral histone deacetylase inhibitor resminostat plus S-1 versus placebo plus S-1 in biliary tract cancers previously treated with gemcitabine plus platinum-based chemotherapy.
12/2020	Adjuvant and neoadjuvant therapy for biliary tract cancer: a review of clinical trials.
12/2020	nal-IRI+5-FU/LV versus 5-FU/LV in post-gemcitabine metastatic pancreatic cancer: Randomized phase 2 trial in Japanese patients.
11/2019	Gemcitabine plus nab-paclitaxel for locally advanced or borderline resectable pancreatic cancer.
10/2018	Protocol digest of randomized phase II study of modified FOLFIRINOX versus gemcitabine plus nab-paclitaxel combination therapy for locally advanced pancreatic cancer: Japan clinical oncology group study (JCOG1407).
8/2018	New developments in systemic therapy for advanced biliary tract cancer.
5/2018	SLCO1B1 Polymorphism Is a Drug Response Predictive Marker for Advanced Pancreatic Cancer Patients Treated With Gemcitabine, S-1, or Gemcitabine Plus S-1.

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Hiroshi Ishii Research Topics

Disease

47	Pancreatic Neoplasms (Pancreatic Cancer) 09/2022 - 03/2003
36	Neoplasms (Cancer) 12/2020 - 08/2003
20	Hepatocellular Carcinoma (Hepatoma) 07/2019 - 04/2003
15	Infections 01/2022 - 04/2007
14	Idiopathic Pulmonary Fibrosis 07/2022 - 06/2005
14	Interstitial Lung Diseases (Interstitial Lung Disease) 07/2022 - 01/2005
14	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2022 - 05/2006
12	Pneumonia (Pneumonitis) 12/2021 - 05/2004
8	Disease Progression 01/2022 - 02/2007
8	Neutropenia 01/2015 - 12/2005
7	Acquired Immunodeficiency Syndrome (AIDS) 01/2022 - 06/2012
7	Neoplasm Metastasis (Metastasis) 11/2019 - 03/2003
6	Sarcoidosis (Schaumann Disease) 08/2020 - 11/2008
6	Ascites 04/2017 - 03/2003
5	Lung Diseases (Lung Disease) 12/2021 - 03/2005
5	Fatigue 10/2021 - 03/2003
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021 - 10/2003
5	Adenocarcinoma 11/2014 - 10/2005
5	Pulmonary Sarcoidosis 01/2011 - 01/2002
4	HIV Infections (HIV Infection) 01/2022 - 05/2011
4	Liver Diseases (Liver Disease) 01/2021 - 11/2003
4	Cognitive Dysfunction 11/2020 - 02/2009
4	Inflammation (Inflammations) 11/2019 - 04/2007
4	Vomiting 06/2017 - 03/2003
4	Asthma (Bronchial Asthma) 01/2017 - 08/2010
4	Fever (Fevers) 09/2016 - 09/2006
4	Alzheimer Disease (Alzheimer's Disease) 11/2015 - 07/2008
4	Anorexia 01/2013 - 03/2003
4	Dementia (Dementias) 05/2012 - 02/2009
4	Pulmonary Eosinophilia (Eosinophilic Pneumonia) 01/2010 - 10/2005
3	Fibrosis (Cirrhosis) 07/2022 - 10/2003
3	Virus Diseases (Viral Diseases) 01/2022 - 12/2014
3	Respiratory Tract Diseases (Respiratory Tract Disease) 10/2021 - 09/2004
3	Communicable Diseases (Infectious Diseases) 01/2021 - 01/2015
3	Dyspnea (Shortness of Breath) 01/2021 - 10/2005
3	Human Influenza (Influenza) 01/2021 - 09/2010
3	Bronchiectasis 09/2019 - 06/2007
3	Rheumatoid Arthritis 01/2019 - 01/2010
3	Hypertension (High Blood Pressure) 01/2019 - 04/2014
3	Exanthema (Rash) 06/2017 - 01/2008
3	Thrombocytopenia (Thrombopenia) 06/2017 - 08/2010
3	Granuloma 09/2016 - 01/2002
3	Respiratory Insufficiency (Respiratory Failure) 09/2016 - 12/2010
3	Trichosporonosis 01/2015 - 01/2007
3	Gallbladder Neoplasms (Gallbladder Cancer) 06/2014 - 01/2004
3	Eosinophilia 10/2012 - 10/2005
3	Nausea 08/2010 - 03/2003
2	Body Weight (Weight, Body) 07/2022 - 01/2021
2	COVID-19 01/2022 - 01/2021

Drug/Important Bio-Agent (IBA)

41	Gemcitabine FDA Link 01/2022 - 01/2005
19	Pharmaceutical PreparationsIBA 01/2021 - 10/2005
11	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 04/2005
10	Biomarkers (Surrogate Marker)IBA 01/2021 - 04/2005
9	VaccinesIBA 01/2022 - 11/2011
9	Fluorouracil (Carac)FDA LinkGeneric 10/2018 - 03/2003
7	Anti-Bacterial Agents (Antibiotics)IBA 12/2021 - 01/2007
7	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2016 - 11/2006
6	EnzymesIBA 06/2022 - 04/2005
6	Proteins (Proteins, Gene)FDA Link 03/2022 - 10/2003
6	Irinotecan (Camptosar)FDA LinkGeneric 10/2018 - 03/2007
6	AntigensIBA 01/2016 - 01/2004
5	PlatinumIBA 01/2021 - 01/2007
5	MacrolidesIBA 01/2021 - 09/2004
5	Peptides (Polypeptides)IBA 01/2017 - 11/2006
5	TegafurIBA 03/2011 - 08/2005
4	AntibodiesIBA 01/2022 - 08/2006
4	EpitopesIBA 01/2022 - 11/2011
4	Clarithromycin (Biaxin)FDA LinkGeneric 01/2021 - 01/2010
4	Sorafenib (BAY 43-9006)FDA Link 08/2018 - 01/2008
4	SteroidsIBA 01/2018 - 01/2007
4	S 1 (combination)IBA 01/2018 - 12/2010
4	Donepezil (Aricept)FDA LinkGeneric 11/2015 - 07/2008
4	C-Reactive ProteinIBA 01/2015 - 02/2007
4	Prednisolone (Predate)FDA LinkGeneric 01/2012 - 10/2005
4	UracilIBA 03/2011 - 08/2005
4	CollagenIBA 04/2007 - 07/2002
3	Neutralizing AntibodiesIBA 01/2021 - 01/2021
3	CytokinesIBA 01/2021 - 03/2005
3	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 01/2018
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2018 - 01/2018
3	folfirinoxIBA 10/2018 - 11/2014
3	miriplatinIBA 02/2018 - 05/2012
3	Interferon-gamma (Interferon, gamma)IBA 09/2016 - 09/2005
3	ORALIT (ORS)IBA 07/2016 - 01/2014
3	AIDS VaccinesIBA 11/2015 - 05/2011
3	InterferonsIBA 01/2012 - 01/2008
2	nintedanibIBA 07/2022 - 01/2021
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2021 - 01/2020

Therapy/Procedure

42	Drug Therapy (Chemotherapy) 09/2022 - 03/2003
32	Therapeutics 12/2020 - 01/2005
11	Radiotherapy 01/2021 - 03/2003
9	Chemoradiotherapy 02/2021 - 03/2003
8	Combination Drug Therapy (Combination Chemotherapy) 02/2022 - 01/2005
4	Immunotherapy 11/2019 - 01/2008
4	Aftercare (After-Treatment) 04/2015 - 10/2005
3	Palliative Care (Palliative Therapy) 09/2022 - 03/2006
3	Induction Chemotherapy 02/2021 - 08/2010
3	Traction 09/2019 - 06/2007
3	Hepatectomy 03/2008 - 11/2006
2	Stents 02/2022 - 07/2013